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How can we make our lab tests of new drugs more realistic to shorten the time to human trials? Plus how can we better test for cancer treatment effectiveness using liquid biopsies? This week we investigate ways to make cancer treatments more effective, and how to better simulate the complexities of the human before before we test a new drug.
Image: Ed Uthman from Houston, TX, USA, 2010, "Mycobacterial Infection, Duodenum". ​Sources: 1. Debora Bonvin et al. Protein Corona: Impact of Lymph Versus Blood in a Complex In Vitro Environment, Small (2017). DOI: 10.1002/smll.201700409 2. Parikh A, Goyal L, Hazar-Rethinam M. Systematic liquid biopsy identifies novel and heterogeneous mechanisms of acquired resistance in gastrointestinal (GI) cancer patients. Ann Oncol 2017; 28 (suppl_3): mdx262. doi: 10.1093/annonc/mdx262.
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March 2020
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